After the initial 50-mile cargo check, what uninterrupted driving interval requires another inspection?
Correct answer: C – 3 hours or 150 miles, whichever occurs first
Federal regulations require cargo and load-securement devices to be reexamined after three hours of driving or 150 miles, whichever occurs first. A change in the driver's duty status can require an earlier inspection. Cargo must also be inspected within the first 50 miles after beginning the trip, subject to the exceptions for certain sealed or impracticable-to-inspect loads.
Source: Colorado Commercial Driver License Manual — § 3.1, “Inspecting Cargo”, 49 CFR § 392.9(b)(2)–(4) — Inspection of cargo, cargo securement devices and systems

